Its use includes treatment for acute pain, such as in severe physical trauma, myocardial infarction, post-surgical pain, and chronic pain, including end-stage cancer and other terminal illnesses.
In other countries it is more common to use morphine or other strong opioids in these situations.
The original trade name of heroin is typically used in non-medical settings.
It is used as a recreational drug for the euphoria it induces.
It is only prescribed following exhaustive efforts at treatment via other means.Equipotent injected doses had comparable action courses, with no difference in subjects' self-rated feelings of euphoria, ambition, nervousness, relaxation, drowsiness, or sleepiness. Single date berlin Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine.If this file has problems with attribution, copyright, or is otherwise ineligible for Commons, then remove this tag and DO NOT transfer it; repeat violators may be blocked from editing.This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.
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The advantage of diamorphine over morphine is that diamorphine is more fat soluble and therefore more potent by injection, so smaller doses of it are needed for the same effect on pain.Both of these factors are advantageous if giving high doses of opioids via the subcutaneous route, which is often necessary in palliative care.By analyzing a community in San Francisco, they demonstrated that heroin use was caused in part by internal and external factors such as violent homes and parental neglect.This lack of emotional, social, and financial support causes strain and influences individuals to engage in deviant acts, including heroin usage.In particular, users report an intense rush, an acute transcendent state of euphoria, which occurs while diamorphine is being metabolized into 6-monoacetylmorphine (6-MAM) and morphine in the brain.
Some believe that heroin produces more euphoria than other opioids; one possible explanation is the presence of 6-monoacetylmorphine, a metabolite unique to heroin – although a more likely explanation is the rapidity of onset.When compared to the opioids hydromorphone, fentanyl, oxycodone, and pethidine (meperidine), former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to abuse and addiction.Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids.While other opioids of recreational use produce only morphine, heroin also leaves 6-MAM, also a psycho-active metabolite.However, this perception is not supported by the results of clinical studies comparing the physiological and subjective effects of injected heroin and morphine in individuals formerly addicted to opioids; these subjects showed no preference for one drug over the other.